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Lugar de nacimiento / Place of birth

Quilmes, Buenos Aires

Fecha de nacimiento / Date of birth

7/12/1977

Contacto / Contact

gmazzone@austral.edu.ar
Últ. actualización: 29/01/2024

Mazzone, Graciela

Instituto de Investigaciones en Medicina Traslacional (IIMT)
Dedicación Exclusiva
Investigador adjunto CONICET
Biología, Biología Celular y Molecular, Bioquímica y biología molecular, Ciencias Médicas
El contenido de este perfil es responsabilidad exclusiva del docente investigador.

Artículos en Revistas CientíficasPapers in Scientific Journals

  1. Sámano C, Mazzone GL. The role of astrocytes response triggered by hyperglycemia during spinal cord injury. Archives of Physiology and Biochemistry, 2023 Oct 05. http://dx.doi.org/10.1080/13813455.2023.2264538.
  2. Mohammadshirazi A, Apicella R, Zylberberg BA, Mazzone GL, Taccola G. Suprapontine Structures Modulate Brainstem and Spinal Networks. Cell Mol Neurobiol. 2023 Feb 2. doi: 10.1007/s10571-023-01321-z. Online ahead of print.
  3. Mazzone GL*, Coronel MF, Mladinic M, Sámano C*. An update to pain management after spinal cord injury: from pharmacology to circRNAs. Rev Neurosci. 2022 Nov 10. doi: 10.1515/revneuro-2022-0089. Online ahead of print. * Joint as corresponding authors.
  4. Glavac D, Mladinic M , Jelena Ban J, Mazzone GL, Sámano C , Tomljanovic I, Jezernik G and Ravnik-Glava M. The Potential Connection between Molecular Changes and Biomarkers Related to ALS and the Development and Regeneration of CNS. Int. J. Mol. Sci. 2022, 23, 11360. https://doi.org/10.3390/ijms231911360.
  5. Borda M; Mazzone GL, Aquino JB. Cell-based experimental strategies for myelin repair in multiple sclerosis. Journal of Neuroscience Research. Septiembre 2022. https://doi.org/10.1002/jnr.25129
  6. Sámano C*, Mladinic M, Mazzone GL*. * Joint as corresponding authors. Circular RNAs: the novel actors in pathophysiology of spinal cord injury. Frontiers In Integrative Neuroscience 2021. Manuscript Accepted.
    Miguel CA, Noya-Riobó MV, Mazzone GL, Villar MJ, Coronel MF. Antioxidant, anti-inflammatory and neuroprotective actions of resveratrol after experimental nervous system insults. Special focus on the molecular mechanisms involved. Neurochem Int. 2021 Sep 16;150:105188. doi: 10.1016/j.neuint.2021.105188. Online ahead of print
  7. Kaur J*, Mazzone GL*, Aquino JB and Andrea Nistri A. * Joint as corresponding authors. Nicotine Neurotoxicity Involves Low Wnt1 Signaling in Spinal Locomotor Networks of the Postnatal Rodent Spinal Cord. Int. J. Mol. Sci. 2021, 22(17), 9572; https://doi.org/10.3390/ijms22179572.
  8. Di Mauro GC, De Ambrosi B, Uchitel OD, Mazzone GL. Case report of neuron-binding IgGs in ALS patient serum in Argentina. J Neurol Neurocrit Care. 2021 Volume 4(2): 1-5. DOI Link: https://doi.org/10.31038/JNNC.2021423
  9. Mazzone GL, Mohammadshirazi A, Aquino JB, Nistri A, Taccola G. GABAergic Mechanisms Can Redress the Tilted Balance between Excitation and Inhibition in Damaged Spinal Networks. Mol Neurobiol. 2021 Apr 7. doi: 10.1007/s12035-021-02370-5. Online ahead of print.
  10. Sierra R, Gómez Bustillo S, Kameneva P, Fiore EJ, Mazzone GL, Borda M, Blanco MV, Usuardi C, Furlan A, Ernfors P, Alaniz L, Montaner AD, Adameyko I, Aquino JB. Contribution of neural crest and GLAST+ Wnt1+ bone marrow pericytes with liver fibrogenesis and/or regeneration. Liver Int. 2020 Apr;40(4):977-987. doi: 10.1111/liv.14401. Epub 2020 Feb 21.
  11. Mazzone GL, Nistri A. Modulation of extrasynaptic GABAergic receptor activity influences glutamate release and neuronal survival following excitotoxic damage to mouse spinal cord neurons. Neurochem Int. 2019 Sep;128:175-185. doi: 10.1016/j.neuint.2019.04.018. Epub 2019 Apr 30.
  12.  Bertone NI, Groisman AI, Mazzone GL, Cano R, Tabares L, Uchitel OD. Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction.  Synapse. 2017 Dec, 71(12). ISSN: 0887-4476 (Print), 1098-2396 (Electronic)
  13. Mazzone GL, Veeraraghavan P, Gonzalez-Inchauspe C, Nistri A, Uchitel OD. ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury. Neuroscience. 2017, Feb 20; 343: 398-410. ISSN: 0306-4522 (Print), 1873-7544 (Electronic).
  14. Mazzone GL, Nistri A. S100β as an early biomarker of excitotoxic damage in spinal cord organotypic cultures. J Neurochem. 2014, Aug;130 (4): 598-604. ISSN: 0022-3042 (Print) 1471-4159 (Electronic), 0022-3042 (Linking).
  15. Mladinic M, Bianchetti E, Dekanic A, Mazzone GL, Nistri A. ATF3 is a novel nuclear marker for migrating ependymal stem cells in the rat spinal cord. Stem Cell Res. 2014 Mar 30;12(3):815-827. ISSN: 1873-5061 (Print), 1876-7753 (Electronic).
  16. Mazzone GL, Mladinic M, Nistri A. Excitotoxic cell death induces delayed proliferation of endogenous neuroprogenitor cells in organotypic slice cultures of the rat spinal cord. Cell Death Dis. 2013. Oct 31;4:e902. ISSN: 2041-4889 (Electronic).
  17. Deumens R*, Mazzone GL*, Taccola G. * Joint as first authors.  Early spread of hyperexcitability to caudal dorsal horn networks after a chemically-induced lesion of the rat spinal cord in vitro. Neuroscience. 2012. Jan 15;229:155-63. ISSN:0306-4522(Print), 1873-7544 (Electronic).
  18. Mazzone GL, Nistri A. Continuous monitoring of endogenous glutamate release with a microelectrode biosensor to study early pathophysiology of spinal injury and to test neuroprotective strategies. 2012. May. Sarissa Biomedical Newsletter. www.sarissa-biomedical.com
  19. Cifra A*,Mazzone GL*, Nistri A*  Joint as first authors. Riluzole: What It Does to Spinal and Brainstem Neurons and How It Does It. The Neuroscientist. 2012, Apr;19(2):137-44. ISSN: 1073-8584 (Print), 1089-4098 (Electronic).
  20. Cifra A*,Mazzone GL*, Nani F, Nistri A, Mladinic M. * Joint as first authors. Postnatal developmental profile of neurons and glia in motor nuclei of the brainstem and spinal cord, and its comparison with organotypic slice cultures. Dev Neurobiol. 2011, Aug;72(8):1140-60. ISSN: 1932-8451(Print), 1932-846X (Electronic).
  21. Kuzhandaivel A, Nistr A, Mazzone GL, Mladinic M. Molecular mechanisms underlying cell death in spinal networks in relation to locomotor activity after acute injury in vitro. Front. Cell. Neurosci. 2011 Jun 17; (5), article 9. ISSN: 1662-5102.
  22. Mazzone GL, Nistri A. Delayed neuroprotection by riluzole against excitotoxic damage evoked by kainate on rat organotypic spinal cord cultures. Neuroscience. 2011. Sep 5 (190); 318–327. ISSN:0306-4522(Print), 1873-7544 (Electronic).
  23. Mazzone GL, Nistri A. Electrochemical detection of endogenous glutamate release from rat spinal cord organotypic slices as a real-time method to monitor excitotoxicity. J Neurosci Methods. 2011 Feb 7.197(1); 128-132.  ISSN 0165-0270 (Print),1872-678X (Electronic).
  24. Mazzone GL, Nistri A. Effect of the PARP-1 Inhibitor PJ 34 on Excitotoxic Damage Evoked by Kainate on Rat Spinal Cord Organotypic Slices. Cell Mol Neurobiol. 2010 Dec 29. 2011(31): 469-478. ISSN 0272-4340 (Print),  1573-6830 (Electronic).
  25. Mazzone GL, Rigato I, Tiribelli C. Unconjugated bilirubin modulates nitric oxide production via iNOS regulation. Biosci Trends. 2010 Oct;4(5):244-8. ISSN 1881-7815 (Print), 1881-7823 (Electronic).
  26. Mazzone GL*, Margaryan G*, Kuzhandaivel A, Nasrabady SE, Mladinic M, Nistri A. * Joint as first authors.  Kainate-induced delayed onset of excitotoxicity with functional loss unrelated to the extent of neuronal damage in the in vitro spinal cord. Neuroscience. 2010 Jun 30;168(2):451-62. Epub 2010 Apr 1. ISSN:0306-4522(Print), 1873-7544 (Electronic).
  27. Mazzone GL, Rigato I, Ostrow JD, Tiribelli C. Bilirubin effect on endothelial adhesion molecules expression is mediated by the NF-κB signaling pathway. BioScience Trends. 2009; 3(4):151-157. ISSN 1881-7815 (Online ISSN 1881-7823).
  28. Mazzone GL, Rigato I, Ostrow JD, Bossi F, Bortoluzzi A, Sukowati CH, Tedesco F, Tiribelli C. Bilirubin inhibits the TNFalpha-related induction of three endothelial adhesion molecules. Biochem Biophys Res Commun. 2009 Aug 21;386(2):338-44. Epub 2009 Jun 10. ISSN 1090-2104
  29. Gualtieri AF, Mazzone GL, Rey R, Schteingart HF. FSH and bFGF stimulate the production of glutathione in cultured rat Sertoli cells. Int J Androl 2009 Jun;32(3):218-25. Epub 2007 Nov 27. ISSN 0105-6263.
  30. Calligaris S,Cekic D, Roca-Burgos L, Gerin F, Mazzone G, Ostrow JD, Tiribelli C. Multidrug resistance associated protein 1 protects against bilirubin-induced cytotoxicity. FEBS Lett. 2006 Feb 20;580(5):1355-9. Epub 2006 Jan 26. ISSN: 0014-5793