Mariana Malvicini She holds a degree in Biochemistry from the University of Buenos Aires (2004) and after training at the Institute of Research in Genetic Engineering and Molecular Biology and the Nuclear Regulatory Authority, she entered the doctoral program at this institution (2007).
She holds a PhD in Biomedical Sciences from the Universidad Austral (2011)
Until the end of 2019, he was part of the Gene Therapy Laboratory at the Faculty of Biomedical Sciences of this University, developing a line of research on the modulation of the antitumor immune response with different strategies in tumors of gastrointestinal origin.
She is currently a member, as an Independent Researcher, of the National Council for Scientific and Technological Research (CONICET).
She is an Associate Professor in charge of the Chair of Immunology in the Medicine program at the Faculty of Biomedical Sciences of the Universidad Austral and Adjunct Professor in charge of the Chair of Immunology in the Biochemistry program at the National University of Entre Ríos (UNER)
Cancer has profound repercussions on our society and throughout the world. It is defined as a chronic disease characterized by the ability of cells to divide uncontrollably, with the potential to spread to other tissues. When normal cells age or become damaged, they die, and new cells replace them. In cancer, this orderly process goes awry. Thus, cells can divide without interruption and can form malignant tumors. Tumors are also frequently able to evade the immune system, a network of organs, tissues, and specialized cells that protects against infections and other diseases. Although the immune system has the ability to eliminate damaged or abnormal cells, some tumor cells are able to evade it or use it to grow, for example, by recruiting cells that prevent the development of an appropriate immune response.
The Cancer Immunobiology Laboratory focuses on studying the tumor microenvironment and developing and optimizing therapies aimed primarily at generating or enhancing an immune response that leads to tumor growth inhibition or eradication. We focus on solid tumors that can arise from tobacco exposure or use, mainly lung cancer and head and neck cancer.
In this context, the laboratory maintains an interdisciplinary activity with physicians who are members of the Oncology and Thoracic Surgery services of the Austral University Hospital.
Its main objectives and lines of work are:
