Doctores

                               

Cubilla, Marisa (2012).
“Mecanismos Endotelinergicos en las enfermedades degenerativas de la Retina”
Director: Dra. Angela Suburo.

 

Publicaciones:

Cubilla MA, Castañeda MM, Bachor TP, Suburo AM. Glucocorticoid-dependent mechanisms in photoreceptor survival. Adv Exp Med Biol. 2012;723:101-6.

Cubilla MA, Bermúdez V, Marquioni Ramella MD, Bachor TP, Suburo AM. Mifepristone, a blocker of glucocorticoid receptors, promotes photoreceptor death. Invest Ophthalmol Vis Sci. 2013 Jan 14;54(1):313-22.

 

Malvicini, Mariana (2011).
“Modulación de la respuesta Inmunitaria antitumoral mediante el Tratamiento combinado con Ciclofodfamida y la terapia génica con Interleuquina 12”.
Director: Dr. Guillermo Mazzolini.
Co-Director: Dr. Pablo Matar.

Publicaciones:
Atorrasagasti C, Malvicini M, Aquino JB, Alaniz L, Garcia M, Bolontrade M, Rizzo M, Podhajcer OL, Mazzolini G. Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells. Int J Cancer. 2009 Oct 14.

Malvicini M, Rizzo M, Alaniz L, Piñero F, García M, Atorrasagasti C, Aquino JB, Rozados V, Scharovsky OG, Matar P, Mazzolini G. A novel synergistic combination of cyclophosphamide and gene transfer of interleukin-12 eradicates colorectal carcinoma in mice. Clin Cancer Res. 2009 Dec 1;15(23):7256-65.

Malvicini M, Ingolotti M, Piccioni F, Garcia M, Bayo J, Atorrasagasti C, Alaniz L, Aquino JB, Espinoza JA, Gidekel M, Scharovsky OG, Matar P, Mazzolini G. Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12. Mol Oncol. 2011 Jun;5(3):242-55.

                               

                                Atorrasagasti, Catalina (2011).
“Efectos de la Inhibición de la Expresión de SPARC (secreted protein acidic and rich in cysteine) sobre Células Estrelladas Hepáticas. Su papel en la Cirrosis Hepática”
Director: Dr. Guillermo Mazzolini.

 

Publicaciones:

Camino AM, Atorrasagasti C, Maccio D, Prada F, Salvatierra E, Rizzo M, Alaniz L, Aquino JB, Podhajcer OL, Silva M, Mazzolini G. Adenovirus-mediated inhibition of SPARC attenuates liver fibrosis in rats. J Gene Med. 2008 Sep;10(9):993-1004.

Atorrasagasti C, Malvicini M, Aquino JB, Alaniz L, Garcia M, Bolontrade M, Rizzo M, Podhajcer OL, Mazzolini G. Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells. Int J Cancer. 2010 Jun 1;126(11):2726-40.

Atorrasagasti C, Aquino JB, Hofman L, Alaniz L, Malvicini M, Garcia M, Benedetti L, Friedman SL, Podhajcer O, Mazzolini G. SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1 and PDGF. Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G739-48

 

  Luengo Gimeno, Federico (2011)
“Trasplante de Stem Cells de Córnea y Bioadhesivos en la Queratoplastia Laminar”  (2009)
Defendió con éxito su tesis doctoral en Junio. Le falta aprobar materias del doctorado
Director:      Dr. Juan Gallo –
Co-Director: Dr. Oscar Croxatto

Publicaciones:

Luengo Gimeno F, Gatto S, Ferro J, Croxatto JO, Gallo JE. Preparation of platelet-rich plasma as a tissue adhesive for experimental transplantation in rabbits. Thromb J. 2006 Sep 28;4:18.

Luengo Gimeno F, Lavigne V, Gatto S, Croxatto JO, Correa L, Gallo JE. Advances in corneal stem-cell transplantation in rabbits with severe ocular alkali burns. J Cataract Refract Surg. 2007 Nov;33(11):1958-65.

Luengo Gimeno F, Lavigne V, Gatto S, Croxatto JO, Correa L, Gallo JE. One-year follow-up of epithelial corneal cell sheet allografts mounted on platelet poor plasma in rabbits. Mol Vis. 2009 Dec 15;15:2771-9.

Iribarne, Maria (2009).
“Nuevos Reguladores Moleculares de las Barreras Oculares”.
Director: Dra. Angela Suburo
Publicaciones
Iribarne M, Torbidoni V, Julián K, Prestifilippo JP, Sinha D, Rettori V, Berra A, Suburo AM. Cannabinoid receptors in conjunctival epithelium: identification and functional properties.Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4535-44. Epub 2008 Jun 19.
Iribarne M, Ogawa L, Torbidoni V, Dodds CM, Dodds RA, Suburo AM. Blockade of endothelinergic receptors prevents development of proliferative vitreoretinopathy in mice.  Am J Pathol. 2008 Apr;172(4):1030-42. Epub 2008 Feb 29.
Iribarne M, Canto-Soler MV, Torbidoni V, Suburo AM,  Controlling retinal pigment epithelium injury after experimental detachment of the retina. Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1348-54.
Prestifilippo JP, Fernández-Solari, J de la Cal C, Iribarne M, Suburo AM, Rettori V, McCann SM, Elverdin JC.Inhibition of salivary secretion by activation of cannabinoid receptors.  Exp Biol Med (Maywood). 2006 Sep;231(8):1421-9.

 Torbidoni, Ana Vanesa (2009)
“Papel del Sistema Endotelinergico en los Procesos Neurodegenerativos de la Retina” 

Director: Dra. Angela Suburo
Publicaciones
Torbidoni V, Iribarne M, Suburo AM.Endothelin receptors: do they have a role in retinal degeneration? Adv Exp Med Biol.2008;613:399-405. No abstract available.
Torbidoni V, Iribarne M, Suburo AM.Endothelin receptors in light-induced retinal degeneration.Exp Biol Med (Maywood). 2006 Jun;231(6):1095-100
Torbidoni V, Iribarne M, Ogawa L, Prasanna G, Suburo AM. Endothelin-1 and endothelin receptors in light-induced retinal degeneration. Exp Eye Res. 2005 Sep;81(3):265-75

 Coronel, Maria Florencia (2007)
“Trasmisores Peptidérgicos y Gaseosos en la Regulación Periférica del Dolor Neuropatico Moduladores Celulares y Moleculares” 
Director: Dr. Marcelo Villar
Publicaciones
Coronel MF, Delfagot, Musolino PL, Villar MJ, Nitric oxide, production in the rat dorsal root ganglia and espinal cord after sciatic nerve lesion.Journal of Neuropathic pain and Symptom Palliation 1:3-9 (2005)
Aquino JB, Musolino PL, Coronel MF, Villar MJ, Setton-Avruj CP. Nerve degeneration is prevented by a single intraneural apotransferrin injection into colchicine-injured sciatic nerves in the rat. Brain Res. 2006 Oct 30;1117(1):80-91. Epub 2006 Sep 28.
Coronel MF, Musolino PL, Villar MJ. Selective migration and engraftment of bone marrow mesenchymal stem cells in rat lumbar dorsal root ganglia after sciatic nerve constriction. Neurosci Lett. 2006 Sep 11;405(1-2):5-9. Epub 2006 Jun 27.
Musolino PL, Coronel MF, Hökfelt T, Villar MJ. Bone marrow stromal cells induce changes in pain behavior after sciatic nerve constriction. Neurosci Lett. 2007 May 11;418(1):97-101. Epub 2007 Mar 3.
Coronel MF, Brumovsky PR, Hökfelt T, Villar MJ. Differential galanin upregulation in dorsal root ganglia and spinal cord after graded single ligature nerve  constriction of the rat sciatic nerve. J Chem Neuroanat. 2008  Jan;35(1):94-100. Epub 2007 Jul 19.
Coronel MF, Musolino PL, Brumovsky PR, Hökfelt T, Villar MJ.Bone marrow stromal cells attenuate      injury-induced changes in galanin, NPY and NPY Y1-receptor expression after a sciatic nerve constriction.Neuropeptides. 2009 Apr;43(2):125-32. Epub 2009 Jan 24.
Coronel MF, Hernando-Insúa A, Rodriguez JM, Elias F, Chasseing NA, Montaner AD, Villar MJ. Oligonucleotide IMT504 reduces neuropathic pain after peripheral nerve injury.Neurosci Lett. 2008 Oct 17;444(1):69-73. Epub 2008 Jul 23

 

 Musolino, Patricia Leonor (2006)
“Mecanismos Moleculares del Dolor Neuropático en los Procesos Degenerativos del Nervio Periférico”.
Director: Dr. Marcelo Villar
Publicaciones
Musolino PL, Coronel MF, Hökfelt T, Villar MJ.Bone marrow stromal cells induce changes in pain behavior after sciatic nerve constriction.Neurosci Lett. 2007 May 11;418(1):97-101. Epub 2007 Mar 3.
Musolino PL, Etton-Avruj CP, Salis C, Alló M, Bizzozero O, Villar MJ, Soto EF, Pasquini JM, Presence of alpha-globin mRNA and migration of bone marrow cells after sciatic nerve injury suggests their participation in the degeneration/regeneration process. Exp Neurol. 2007 Feb;203(2):568-78. Epub 2006 Nov 28.
Aquino JB, Musolino PL, Coronel MF, Villar MJ, Setton-Avruj CP.Nerve degeneration is prevented by a single intraneural apotransferrin injection into colchicine-injured sciatic nerves in the rat. Brain Res. 2006 Oct 30;1117(1):80-91. Epub 2006 Sep 28
Coronel MF, Musolino PL, Villar MJ.Selective migration and engraftment of bone marrow mesenchymal stem cells in rat lumbar dorsal root ganglia after sciatic nerve constriction. Neurosci Lett. 2006 Sep 11;405(1-2):5-9. Epub 2006 Jun 27.

 

Brumovsky, Pablo (2003)
“Los Neuropéptidos Tirosima, Galanina Sus Receptores y el Dolor Neuropático”.
Director: Dr. Marcelo Villar.
Publicaciones
Matsuda H, Brumovsky PR,  Kopp J, Pedrazzini T, Hökfelt T.Distribution of neuropeptide Y Y1 receptors in rodent peripheral tissues. J Comp Neurol. 2002 Aug 5;449(4):390-404.
Brumovsky PR, Shi TJ, Matsuda H, Kopp J, Villar MJ, Hökfelt T.NPY Y1 receptors are present in axonal processes of DRG neurons. Exp Neurol. 2002 Mar;174(1):1-10.
Brumovsky PR, Berman,  Liu HX, Hökfelt T, Villar MJ, Effect of a graded. Single contriction of the rat sciatic nerve on plain behavier and expression of inmunorractive NPY and NPY Y1 receptor in DRG neurons and spinal cord. Brain Res. 2004 Apr 23;1006(1):87-99
Liu HX, Brumovsky P, Schmidt R, Brown W, Payza K, Hodzic L, Pou C, Godbout C, Hökfelt T.
Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective     actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4. Epub 2001 Jul 31.

Canto Soler, Maria Valeria (2002)

“Neuromediadores en la Proliferación Vitreoretinal” 

Director: Dra. Angela Suburo
Publicaciones
Cantó Soler MV, Gallo JE, Dodds RA, Suburo AM, Mouse model of proliferative vitreoretinopathy induced by dispase.  Exp Eye Res. 2002 Nov;75(5):491-504
Cantó Soler MV, Gallo JE, Dodds RA, Hökfelt T, Villar MJ, Suburo AM.Y1 receptor of neuropeptide Y as a glial marker in proliferative vitreoretinopathy and diseased human retina. Glia. 2002 Sep;39(3):320-4